Congratulations Dr. Sau!

Míriam Sau, PhD student under the supervision of Profs. Miquel A. Pericàs and Rubén Martín, has defended her PhD Thesis entitled ‘From Click Chemistry to Catalytic Cleavage of Unstrained C-C Bonds’ (assigned to the Organic and Analytical Chemistry Department of the Universitat Rovira i Virgili) publicly on July 21st at the ICIQ auditorium.

The members of the evaluation committee were: Prof. Albert Moyano Baldoire (Universitat de Barcelona), Prof. María Elena Fernández Gutiérrez (Universitat Rovira i Virgili) and Prof. Florenci González Adelantado (Universitat Jaume I).

Dr. Sau with her supervisors, Profs. Miquel À. Pericàs and Rubén Martín, and the evaluation committee

Abstract:

In this PhD thesis, different methodologies have been used for the synthesis of different small molecules bearing interesting scaffolds for research. Specifically, a Cu-free 1,3-dipolar cycloaddition reaction was developed using t-BuOH/H₂O under microwave irradiation for the synthesis of triazoles fused to seven membered rings. Additionally, we have implemented a catalytic functionalization of unstrained C–C bonds of 1,2-amino acids, resulting in a formal b-arylation of aldehydic counterparts.