SYNFACTS selects the most significant results on synthetic organic chemistry that appear in the literature considered as the future trends in synthetic chemistry.

Two ICIQ papers published by the groups of Paolo Melchiorre and Carles Bo in the Journal of the American Chemical Society and Antonio Echavarren’s team in Angewandte Chemie International Edition have been highlighted in Synfacts Issue 8.

Melchiorre and Bo’s paper describes a stereochemical model for Cinchona-Derived Primary Amine Catalysts through a combination of experimental and theoretical mechanistic studies.

A. Moran, A. Hamilton, C. Bo, P. Melchiorre

J. Am. Chem. Soc., 2013, 135, 9091-9098

The paper published by Echavarren’s research group reveals the total synthesis of antiviral (+)-Schisanwilsonene A along with the assignment of its absolute configuration.

M. Gaydou, R.E. Miller, N. Delpont, J. Ceccon, A.M. Echavarren

Angew. Chem. Int. Ed., 2013, 52, 6396-6399