Strem Chemicals Inc. sells organocatalysts synthesised through a new synthetic route developed at ICIQ

CSOL, in collaboration with Prof Melchiorre, has developed a new synthetic route to obtain eight previously known cinchona alkaloid derivatives used as organocatalysts for a broad range of reactions.

This new synthetic method, which has been protected by ICIQ through patent application, has a much lower economic cost allowing for the commercialisation of the compounds at a more competitive price.

Four of these compounds prepared through this route can be now purchased from Strem at nearly half the price than other suppliers.

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Applications

These compounds are effective asymmetric organocatalysts able to stereoselectively functionalise hindered carbonyl compounds (simple ketones as well as α-branched substituted aldehydes and ketones and their α, β-unsaturated counterparts).

The use of these asymmetric organocatalysts will help  to obtain libraries of new organic compounds for the synthesis of biologically active compounds (pharmaceuticals and agrochemicals) as well as specialty materials.

CSOL (Catalytic Solutions)

CSOL is a technology development unit integrated in the Institute of Chemical Research of Catalonia (ICIQ).
It offers innovative, tailor-made catalytic solutions for homogeneous transformations, including enantioselective reactions.
CSOL’s mission is to act as the link between the researchers’ expertise and the industry, as well as developing the researchers’ discoveries into industrial applications with a comprehensive approach.