Carlo Cassani

PhD Student

FPI PhD fellow (BES-2011-044203)

Title of the Thesis: “Aminocatalytic Functionalization of Carbonyl Compounds: a Powerful Strategy for Enantioselective Reaction Development”, Defense: 16-Dec-2013

Publications at ICIQ

• Mattia Silvi, Elena Arceo, Igor Jurberg, Carlo Cassani, and Paolo Melchiorre, “Enantioselective Organocatalytic Alkylation of Aldehydes and Enals Driven by the Direct Photoexcitation of Enamines“, J. Am. Chem. Soc. 2015, 137, 6120–6123
• Carlo Cassani, Rafael Martín-Rapún, Elena Arceo, Fernando Bravo and Paolo Melchiorre, “Synthesis of 9-amino(9-deoxy)epi cinchona alkaloids, general chiral organocatalysts for the stereoselective functionalization of carbonyl compounds“, Nature Protocols 2013, 8, 325-344
• Carlo Cassani, and Paolo Melchiorre, “Direct Catalytic Enantioselective Vinylogous Aldol Reaction of α-Branched Enals with Isatins,” Org. Lett. 2012, 14 (21), 5590–5593
• M. Silvi, C. Cassani, A. Moran, and Paolo Melchiorre, “Secondary amine-catalyzed asymmetric gamma-alkylation of alpha-branched enals via dienamine  activation“, Helvetica Chim. Acta 2012, 95, 1985-2006
• X. Tian, C. Cassani, Y. Liu, A. Moran, A. Urakawa, P. Galzerano, E. Arceo, and P. Melchiorre, “Diastereodivergent Asymmetric Sulfa-Michael Additions of α-Branched Enones using a Single Chiral Organic Catalyst”, J. Am. Chem. Soc. 2011, 133, 17934–17941
• C. Cassani, X. Tian, E. C. Escudero-Adán, and P. Melchiorre, “Multiple approaches to enantiopure spirocyclic benzofuranones using organocatalytic cascade reactions“, Chem. Comm. 2011, 47, 233-235