Stereoselective gold-catalyzed cycloaddition of functionalized ketoenynes: Synthesis of (+)-orientalol F

A stereoselective gold-catalyzed [2 + 2 + 2] cycloaddition of ketoenynes substituted at the propargylic position with OR groups has been applied for the synthesis of (+)-orientalol F and pubinernoid B.

(2009 “Catalysis in Organic Synthesis” web theme issue)