AuI-catalyzed cyclizations of functionalized enynes lead to the ready assembly of tricyclic carbon skeletons that are present in a number of naturally occurring compounds. An alkenyl gold intermediate is formed in the cyclization of the enynes and can be trapped in 5-exo-dig or 6-endo-dig Prins reactions to form an additional CC bond. Z=C(CO2Me)2, NTs; R=H, Me, iPr
![Prins cyclizations in Au-catalyzed reactions of enynes](https://www.iciq.org/wp-content/uploads/2014/03/Prins-cyclizations-in_eng_noticies_articles_2006_36.gif)