Ni-catalyzed reduction of inert C-O bonds: A new strategy for using aryl ethers as easily removable directing groups

An efficient Ni-catalyzed protocol for the reductive cleavage of inert C-O bonds has been developed. The method is characterized by its simplicity and wide scope, thereby allowing the use of aryl ethers as easily removable directing groups in organic synthesis.

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Ni-catalyzed reduction of inert C-O bonds: A new strategy for using aryl ethers as easily removable directing groups

P. Álvarez-Bercedo, R. Martin

J. Am. Chem. Soc. 2010, 132, 17352-17353

Associated ICIQ research group/s:

  • RESEARCH GROUP/S
    Prof. Ruben Martin
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