A direct metal-free amination of arylalkynes has been developed, which proceeds by reaction of the terminal alkyne with the hypervalent iodine reagent PhI(OAc)NTs2 within a single-step operation. This unprecedented intermolecular C-H to C-N bond conversion provides rapid access to the important class of ynamides. In addition to the title reaction, the related transformation between alkylated alkynes and the iodine(III) reagent is also discussed.
![Metal-free iodine(III)-promoted direct intermolecular C?H amination reactions of acetylenes](https://www.iciq.org/wp-content/uploads/2014/03/Metal-free-iodineIII_15505.gif)