A tungsten-catalyzed hydroboration of unactivated alkenes at distal C(sp3)–H bonds aided by native directing groups is described herein. The method is characterized by its simplicity, exquisite regio- and chemoselectivity and wide substrate scope, offering a complementary site-selectivity pattern to other metal-catalyzed borylation reactions and chain-walking protocols.
Jankins, T.; Martin-Montero, R.; Cooper, P.; Martin, R.; Engle, K.
J. Am. Chem. Soc. 2021, 143 (37), 14981–14986
DOI:
10.1021/jacs.1c07162
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