A catalytic reductive cleavage of C(sp2)- and C(sp3)-SMe bonds under ligandless conditions is presented. The method is characterized by its wide scope and high chemoselectivity profile including challenging substrate combinations, allowing the design of orthogonal and site-selectivity approaches.
![Ligand-free Ni-catalyzed reductive cleavage of inert carbon-sulfur bonds](https://www.iciq.org/wp-content/uploads/2014/03/Ligand-free-Ni-catalyzed_796.gif)