Dual Catalytic Strategy for Forging sp2–sp3 and sp3–sp3 Architectures via β-Scission of Aliphatic Alcohol Derivatives

A dual platform for forging sp²–sp³ and sp³–sp³ carbon bonds via catalytic β-scission of aliphatic alcohol derivatives with both aryl and alkyl halides is disclosed. This protocol is distinguished by its wide substrate scope and broad applicability, even in the context of late-stage functionalization.