Catalytic asymmetric transfer hydrogenation of rac-furoin and furil produces hydrofuroin with up to 99% ee and 9:1 dr. This reaction provides an exceptionally easy access to optically active hydrofuroins in two straightforward steps from biomass-derived furfural (global production 200 000-300 000 t annually) using benzoin condensation.
![Biomass conversion to high value chemicals: From furfural to chiral hydrofuroins in two steps](https://www.iciq.org/wp-content/uploads/2014/03/Biomass-conversion-to-high_4014.gif)