Gold(I)-catalyzed allene-vinylcyclopropane cycloisomerization leads to the tricyclic framework of the protoilludanes in a single step by a reaction that involves a cyclopropane ring expansion and a Prins cyclization.
![Access to the Protoilludane Core by Gold-Catalyzed Allene-vinylcyclopropane Cycloisomerization](https://www.iciq.org/wp-content/uploads/2014/03/Access-to-the-Protoilludane_ol-2013-02188b_0010.gif)
Gold(I)-catalyzed allene-vinylcyclopropane cycloisomerization leads to the tricyclic framework of the protoilludanes in a single step by a reaction that involves a cyclopropane ring expansion and a Prins cyclization.