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Research on chirality induction from Kleij's research group reaches the back cover on Angew. Chem. Int. Ed.

The article Effective Chirogenesis in a Bis(metallosalphen) Complex through Host-Guest Binding with Carboxylic Acids (Angew. Chem. Int. Ed. 2011, 50, 713-716), authored Sander J. Wezenberg, Giovanni Salassa, Eduardo C. Escudero-Adán, Jordi Benet-Buchholz, and Arjan W. Kleij has been highlighted on the back cover of Angewandte Chemie International Edition.

The authors report that the addition of carboxylic acids to a supramolecular host system based on a metallosalphen framework results in chirality induction. In their communication, they describe how the observed effective chirogenesis is expressed in the circular dichroism spectra of the host-guest system, and can lead to new and improved methodologies for the determination of absolute configurations.