Room-temperature activation of aryl chlorides in Suzuki-Miyaura coupling using a [Pd(μ-Cl)Cl(NHC)]2 complex (NHC = N-heterocyclic carbene)

A straightforwardly synthesised complex, [Pd(nu-Cl)Cl(NHC)]₂ (NHC = bis(2,6-diisopropylphenyl)imidazol-2-ylidene, IPr), has been employed to mediate Suzuki-Miyaura reactions involving aryl chlorides at very low catalyst loadings and at room temperature.