Alkyliodines in High Oxidation State: Enhanced Synthetic Possibilities and Accelerated Catalyst Turn‐Over

In contrast to aryliodine(III) compounds, which have matured into a particularly attractive class of oxidants in modern synthesis, the synthetic potential of related alkyliodine(III) derivatives has remained widely underestimated. This is surprising since several unique synthetic possibilities arise directly from the low stability of their central carbon–iodine bond. In this respect, these high‐oxidation‐state iodine compounds resemble environmentally benign variants of the prominent metal counterparts such as those derived from palladium, nickel and copper. This Concept article summarizes the general reactivity trends in alkyliodine(III) chemistry and discusses selected examples of their strategic use as highly reactive, transient species in organic synthesis and homogeneous catalysis.

Random publication image

Bosnidou, A. E.; Muñiz, K.

Chem.: Eur. J 2019, 25, (60), 13654-13664
DOI: 10.1002/chem.201902687

  • SHARE

Let's create a brighter future

Join our team to work with renowned researchers, tackle groundbreaking
projects and contribute to meaningful scientific advancements

Join us!
Board of Trustees:
Member of:
Accredited with:
With the support of: