Paolo Melchiorre et al. paper highlighted in Synfacts

The paper on photochemical α-alkylation of aldehydes published by Paolo Melchiorre and his research team in Nature Chemistry Issue 5 has been highlighted in the latest issue of Synfacts.

The paper describes an innovative strategy that uses visible light to activate chiral enamines and promote the formation of new carbon bonds in high yields with high enantioselectivity.

This new photochemical method has been selected by the Editorial Board of Synfacts and is enriched with comments by Benjamin List and Gabriele Pupo.

Other media sources have reported on these results.

Photochemical activity of a key donor–acceptor complex can drive stereoselective catalytic α-alkylation of aldehydes
E. Arceo, I.D. Jurberg, A. álvarez-Fernández, P. Melchiorre
Nat. Chem., 2013, 5, 750-756

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