The paper by Ruben Martin and Arkaitz Correa describes a novel Ni-catalyzed reductive amidation of C(sp2)-O and C(sp3)-O electrophiles with isocyanates. This umpolung reaction allows for an unconventional preparation of benzamides using simple starting materials and easy-to-handle Ni catalyst.
Ni-Catalyzed Direct Reductive Amidation via C-O Bond Cleavage
Arkaitz Correa and Ruben Martin
J. Am. Chem. Soc, 2014, 136 (20), pp 7253-7256
This paper has been the most read article of JACS in May. Actually, every single paper published by Ruben Martin’s group in JACS in 2014 has been a JACS most read paper (JACS 2014, 136, 1062-1069, JACS 2014, 136, 2236-2239 and JACS 2014, 136, 7253-7256).
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