The KTT-MedChem Unit is specialised in the development of drug discovery and medicinal chemistry projects in collaboration with pharmaceutical companies and biomedical research institutions. Our expertise spans across early stage hit finding to clinical candidate discovery.

The MedChem Unit counts with highly qualified PhD scientific personnel, with extended experience in the development of medicinal chemistry projects, and the ICIQ state-of-art equipment and resources to offer high-quality and optimal solutions for Medicinal Chemistry projects.

We have significant expertise in the optimisation of HTS hits and lead compounds, taking into account principles of IP, lead-likeness, synthetic feasibility and ADME properties. Wherever appropriate, computational chemistry capabilities are used in ligand- and structure-based methods, in order to prioritise new compounds to be synthesised.

Parallel synthesis and semiautomated purification systems enable the synthesis of chemical libraries for hit and lead optimisation. Additionally, the possibility of using ICIQ-High Throughput Experimentation (HTE) technology can accelerate the discovery and implementation of new and efficient synthetic methodologies.