Prof. Marcos García Suero

The main objective is to discover and develop new reactivity concepts in C-H and C-C bond functionalization through the catalytic generation of unexplored and underappreciated reactive species. We have pioneered the catalytic generation of diazomethyl radicals and Rh-carbynoids as carbyne equivalents, which allowed us to discover novel late-stage functionalizations of complex natural products and drug molecules as well as skeletal editing processes. We are also interested in high-throughput techniques for the synthesis of libraries of bioactive molecules, development of new radiolabelling reactions to impact PET imaging and precision medicine as well as new reagents for site-selective bioconjugations of biomamacromolecules to impact chemical biology.