DESign of Chemoenzymatic and Main-Group-Mediated (RLi) Organic Transformations in Water and Deep Eutectic Solvents (DESs)

New cleaner and more efficient organic transformations in green solvents [i.e., water or Deep eutectic Solvents (DESs)] are emerging as exciting alternatives to traditional organic transformations based on the use of volatile and hazardous organic solvents (VOCs). In this sense, we have studied the employment of the aforementioned sustainable solvents in: i) transition-metal-catalyzed organic reactions; ii) the chemoselective addition of highly-polarized organometallic reagents (RLi) in DESs, at room temperature and under air; and iii) the combination of metal-catalyzed organic reactions (isomerizations or cycloisomerizations) with enzymes. Thus, in this seminar, we will present our findings in this field of chemistry during the last five years.