Abstract

An increased utilization of feedstock materials in catalytic endeavours holds great promise to revolutionize approaches in organic synthesis for preparing added-value building blocks. In this regard, catalytic protocols for incorporating carbon dioxide (CO₂) into organic matter has recently attracted considerable attention in carbon-carbon bond-forming reactions.¹ Among the different alternatives, the ability to design catalytic CO₂ fixation en route to carboxylic acids would be particularly appreciated, as these motifs are important structural elements in a myriad of pharmaceuticals and agrochemicals, among others.^2,3 In recent years, our research group has reported some progress directed towards the catalytic reductive carboxylation of organic matter with CO₂ (Scheme 1).⁴ These methods are characterized by their simplicity, wide substrate scope, including challenging substrate combinations with particularly sensitive functional groups and a diverse set of substitution patterns.