The fascinating molecular motors and machines that sustain life offer a great source of inspiration to the molecular explorer at the nanoscale. Among the major challenges ahead in the design of complex artificial molecular systems is the control over dynamic functions and responsive far-from-equilibrium behaviour. Chemical systems ultimately require integration of structure, organization and function of multi-component dynamic molecular assemblies at different hierarchical levels. A major goal is to achieve and exploit translational and rotary motion.

In this presentation the focus is on the dynamics of functional molecular systems as well as triggering and assembly processes. We design switches and motors in which molecular motion is coupled to specific functions. Responsive behaviour will be illustrated in self- assembly and photopharmacology. The design, synthesis and functioning of rotary molecular motors and machines will also be presented with a prospect toward future dynamic molecular systems.