BioNanoTools: Smart materials for biological applications

Nanotechnology allows the creation of a myriad of materials by producing composite self-assembled architectures, e.g., inorganic and/or organic nano-particles (NPs), biomolecules, therapeutics, etc. The fine tuning over their properties provides with novel, multifunctional tools for drug-delivery applications.

Between nanotechnology and achieving advanced medicinal products stand entangled challenges such as understanding and controlling the biomolecule−NP (biomolecular corona) in vivo; avoiding intracellular degradation of the nano-formulations due to lysosomal/phagolysosome storage; and highly specific targeting of cells and/or tissues.

When designing a nanomedicine some characteristics should be fulfilled to ensure its in vivo success: avoid sequestration by the mononuclear phagocytic system (MPS); and major accumulation in the liver and spleen; present prolonged circulation; targeting abilities to recognize specific cells and tissues; and the ability to perform an action.

This last point can be achieved by developing stimuli-responsive controlled delivery systems triggered by stimuli such as light, ultrasound, magnetic fields, pH, enzymatic catalysis, competitive guests, etc. The interaction of light or alternating magnetic fields with inorganic NPs is orders of magnitude stronger than with organic molecules due to their larger absorption cross-sections. Therefore, inorganic NPs (or hybrid composites) offer a convenient platform to produce remotely controlled colloidal nanosystems. These interactions can be applied to develop nanoheaters, nanoreactors, or to induce a controlled drug release that offers novel and personalized therapy and imaging tools.

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According to the last information received from ICIQ’s safety department about the measures to prevent and contain COVID-19 at ICIQ, a total of 70 people is now the maximum capacity allowed in the Auditorium, so the conference will be finally held in the Auditorium as well as through ZOOM platform too.

If you are interested in attending in the Auditorium, please, fill in this registration form to be sure that we do not exceed the maximum capacity. (It will be assigned on a first-come/first served basis). We will confirm your acceptance through an e-mail 24h before the event.