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A paper from Prof. Pericàs' group, selected by the Editorial Board of SYNFACTS

The article Proline-Derived Aminotriazole Ligands: Preparation and Use in the Ruthenium-Catalyzed Asymmetric Transfer Hydrogenation , authored by Dr. X.C. Cambeiro and Prof. M.A. Pericàs and published in Adv.Synth.Catal. 2011, 353, 113-124, has been selected by the Editorial Board of SYNFACTS for its important insights.

In this work, the authors describe the preparation and catalytic performance of a new class of chiral aminotriazole ligands. In order to examine the catalytic performance of these new ligands, synthesized from cooper-catalyzed click chemistry, they are applied in the ruthenium-catalyzed asymmetric transfer hydrogenation of ketones and good results are obtained after careful optimization.