The first general palladium-catalyzed intermolecular diamination of internal alkenes employs different nitrogen sources, which add to the alkene in a regio- and diastereoselective fashion. The resulting diamination products can be converted directly into a known ligand motif.
![Palladium-catalyzed vicinal difunctionalization of internal alkenes: Diastereoselective synthesis of diamines](https://www.iciq.org/wp-content/uploads/2014/03/Palladium-catalyzed-vicinal_7031.gif)