Ghosting the directing group: A clever design of a nitrile based catalyst directing group, serves as tool in the palladium-catalyzed meta-olefination of phenol derivatives. This group can be removed tracelessly, thus providing a convenient route to meta-substitution of phenols, a transformation that cannot be conducted by classic aromatic substitution chemistry.
![A New Remote Control for Traceless meta-C-H Olefination of Phenols](https://www.iciq.org/wp-content/uploads/2014/03/A-New-Remote-Control_chemcatchem20muniz.gif)