We report the reaction of 4,4′-substituted benzils with squaramides (SQ) affording mono-squarimides (SQIs). The 1H NMR and X-ray structures of the SQIs (R = H) revealed the existence of a strong C=O···HN intramolecular hydrogen-bond motif. The unprecedented reaction between SQs and benzils highlights the difference in reactivity between urea and squaramide units.
E. Sanna, C. López, P. Ballester, C. Rotger, A. Costa
Eur. J. Org. Chem. 2015, 7656-7660
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