Covalently immobilized tris(triazolyl)methanol–Cu(I) complexes: Highly active and recyclable catalysts for CuAAC reactions

Tris(1-benzyl-1H-1,2,3-triazol-4-yl)methanol (3), a highly efficient ligand for CuAAC reactions, has been immobilized onto Merrifield resins through different strategies. The SN2-supported Cu complex (8) is stable in water and under air; it is active at low catalyst loadings (1 mol%) and at low concentration (down to 0.125 M) in both aqueous and purely organic media. Resin 8 can be repeatedly reused in 1:1 MeOH-water for short reaction times (4 h) with the only precaution of Cu(I) reloading every five cycles.

Covalently immobilized tris(triazolyl)methanol–Cu(I) complexes: Highly active and recyclable catalysts for CuAAC reactions

E. Ozkal, S. Özçubukçu, C. Jimeno, M. A. Pericàs

Catal. Sci. Technol. 2012, 2, 195-200
DOI: Go to the journal

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