Photochemical Processes Enabled by the Direct Excitation of Organic Intermediates

The work described in this dissertation focuses on the combination of two powerful molecule activation strategies, organocatalysis and photochemistry.

The photoenolization process is an historical photochemical reaction with known applications in organic synthesis. However, the nucleophilic reactivity of  the photoenol intermediate, arising from the photoenolization mechanism, was never tested with electrophiles such iminines for the devolpment of an asymmetric catalytic Mannich-type type reaction. In the second part of the talk will be discuss the combination of the photochemical reactivity of the iminium ion intermediates and ground state reactivity of enamine intermediates for the development of a photochemical organocascade transformation. In the last part of the talk will be discuss a new catalytic radical generation strategy for the synthesis of boronic derivatives.