The global need to move current human technologies into a sustainable future will have a great impact for the world of chemistry and related industries. In close concert with other disciplines, chemistry will be increasingly solicited to identify solutions that are practical, affordable and ultimately sustainable. To meet these objectives, not only research, but also […]
Driving asymmetric photoreactions by merging organoand gold-catalysis
We are in a changing era for drug discovery: the growing perception is that basic chemical research will play a greater role in pharmaceutical development. One current challenge is to develop a new kind of chemistry that yields a screening collection comprising optimal chiral molecules that increase the probability of success in identifying drug-candidate structures. […]
Photo-Organocatalysis In Asymmetric Synthesis
Light-Driven Asymmetric Organocatalysis
Visible light photocatalysis and metal-free organocatalytic processes are powerful strategies of modern chemical research with extraordinary potential for the sustainable preparation of organic molecules. However, these environmentally respectful approaches have to date remained largely unrelated. The proposed research seeks to merge these fields of molecule activation to redefine their synthetic potential. Light-driven processes considerably enrich […]
Control of Remote Stereochemistry in the Synthesis of Complex Molecules by Means of Vinylogous Organocascade Catalysis
Vinylogous organocascade catalysis to control remote stereochemistry in complex molecules
Chemical Reactivity with Organocatalysis
Visible Light Promoted Enantioselective Addition of α-Amino Radicals to α,β-Unsaturated Carbonyl Compounds
Postdoctoral Fellowship – Luca Dell’Amico
Photo-organocatalytic reactions drive by visible light
Development of new photochemical organocatalytic processes driven by visible light.
Light-driven Enantioselective Organocatalytic Reactions
Remote control of the stereochemistry in the synthesis of complex molecules through the concept of vinylogous organocatalytic cascades
Postdoctoral Fellowship – Hamish Bruce Hepburn
Postdoctoral Fellowship – John Murphy
Developing new organocatalytic approaches to chemical synthesis using novel reactivity concepts
Organo-Cascade Catalysis: A Shortcut to Stereochemical and Molecular Complexity
To impact science and society in the way that we feel is possible, synthetic chemistry needs to combine innovation and execution. We are motivated by the idea that novel chemical methodologies are needed to enable the synthesis of novel, previously elusive natural-like scaffolds. Only innovative organic chemistry research can provide the next generation of problem […]
Merging organo- and gold-catalysis to design cascade reactions: a shortcut toward molecular complexity
We are in a changing era for drug discovery: the growing perception is that basic chemical research will play a greater role in pharmaceutical development. One current challenge is to develop a new kind of chemistry that yields a screening collection comprising optimal chiral molecules that increase the probability of success in identifying drug-candidate structures. […]