A paper published by Prof. Ruben Martin group in Angewandte Chemie International Edition has been highlighted in Synfacts, Vol 10, Issue 12, 1255. Synfacts selects the most significants results on synthetic organic chemistry that appear in the literature considered as the future trends in synthetic chemistry.

The paper deals with the development of a tandem C(sp²)H and C(sp³)H functionalization/CO bond formation catalyzed by iodine(III) reagents generated in situ. The method shows wide scope under mild conditions and exhibits an unprecedented selectivity profile that can be switched depending on the catalyst employed.

 

Mild ArI-Catalyzed C(sp²)H or C(sp³)H Functionalization/CO Formation: An Intriguing Catalyst-Controlled Selectivity Switch
X. Wang, J. Gallardo-Donaire, R. Martin
Angew. Chem. Int. Ed., 53, 11084-11087